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Why is Relaxivity Important?

  • Higher relaxivity could result in*
    • increased signal on T1-weighted images1,2
    • enhanced image quality2
    • improved diagnostic confidence3,4
  • In steady-state imaging, GBCA distribution in tissue** and imaging time point contributes to signal enhancement: higher relaxivity leads to higher signal increase5
  • In dynamic imaging (e.g. MRA), the image is obtained while the GBCA passes through a certain area: local tissue concentration, injected dose and relaxivity impact the signal6,7

  * at equal contrast dose

** e.g. leakage due to blood brain barrier disruption or vascularization

Relationship between higher relaxivity and improved image quality and diagnostic confidence in three steps1,2,8


Next: Relaxivity of Gadovist® Compared to Other Macrocyclic GBCAs